BDBM50195482 (4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-4-(pyridin-2-yl)piperazin-1-yl)methanone::CHEMBL223373

SMILES C[C@H]1CN(C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1)c1ccccn1

InChI Key InChIKey=REVBKPSDCXGBNR-TXEJJXNPSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50195482   

Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataKi:  6nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataKi:  100nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195482((4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed