BDBM50198574 (S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one::(S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one::CHEMBL384400

SMILES CCN(CC)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2ccc(Cl)cc2)CC1=O

InChI Key InChIKey=GIRWMBVCAVUZRN-SANMLTNESA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198574   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198574((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...)
Affinity DataKi:  3.30nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198574((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...)
Affinity DataKi:  4nMAssay Description:Binding affinity at MCHR1 by flash plate radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198574((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198574((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed