BDBM50200480 CHEMBL3965352
SMILES [H][C@]1(CC[C@@H](C)c2ccc(C)nc12)[C@@H](C)C(=O)Nc1ccc(Cl)c(c1)-c1nc2ccccc2n1C
InChI Key InChIKey=JMXYJARAWTZWPL-BLIXFSHQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50200480
Affinity DataEC50: 24nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 50 nM measured after 3...More data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 100 nM measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of Smo-mediated Hh signalling pathway in mouse Shh Light2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 137nMAssay Description:Inhibition of Smo in mouse Shh Light2 cells assessed as inhibition of SAG-induced Hh pathway activity by measuring SAG-EC50 at 500 nM measured after ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Chinese Academy Of Sciences
Curated by ChEMBL
University Of Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair