BDBM50201357 CHEMBL401041::N-(4-tert-butylphenyl)-1-methyl-4-(pyridin-4-ylmethylamino)-1H-pyrazole-5-carboxamide

SMILES Cn1ncc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=YBLAYGHYSZAEPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201357   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201357(CHEMBL401041 | N-(4-tert-butylphenyl)-1-methyl-4-(...)
Affinity DataIC50:  130nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201357(CHEMBL401041 | N-(4-tert-butylphenyl)-1-methyl-4-(...)
Affinity DataIC50:  45nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201357(CHEMBL401041 | N-(4-tert-butylphenyl)-1-methyl-4-(...)
Affinity DataIC50:  180nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed