BDBM50203245 CHEMBL3901807
SMILES Cc1nc(N)nc(N)c1CN1CCN(CC1)c1cccc(c1)-c1cccc(c1)C#N
InChI Key InChIKey=KKSNKORHYYLJIP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50203245
Affinity DataIC50: 920nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli preincubated for 15 mins followed by addition of DHF as substrate and NADPH measur...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Turing Pharmaceuticals
Curated by ChEMBL
Turing Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADP...More data for this Ligand-Target Pair