BDBM50208359 5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic acid)::5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-biphenyl-3-carboxylic acid::CHEMBL228397

SMILES OC(=O)c1cc(Cc2cc(C(O)=O)c(O)c(c2)-c2ccccc2)cc(c1O)-c1ccccc1

InChI Key InChIKey=NPOVMAFHVDLXQA-UHFFFAOYSA-N

Data  3 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50208359   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of SHP-1 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase 1(Saccharomyces cerevisiae)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  2.34E+5nMAssay Description:Inhibition of yeast PTP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of SHP-1 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of PTP SHP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  2.91E+5nMAssay Description:Inhibition of TC-PTP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5,5'-methylenebis(2-hydroxybiphenyl-3-carboxylic a...)
Affinity DataIC50:  2.91E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed