BDBM50209360 CHEMBL230255::N-(3-methyl-4-(1-methylpiperidin-4-yloxy)phenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine

SMILES Cc1cc(Nc2ncnc3ccc(OCCCN4CCOCC4)cc23)ccc1OC1CCN(CC1)C(=O)CC(C)(C)C

InChI Key InChIKey=NKYZLAFGFAJBIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209360   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209360(CHEMBL230255 | N-(3-methyl-4-(1-methylpiperidin-4-...)
Affinity DataIC50:  75nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209360(CHEMBL230255 | N-(3-methyl-4-(1-methylpiperidin-4-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed