BDBM50211342 2,4-dichloro-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)benzenesulfonamide::CHEMBL391035

SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=KAHFZGUOPFFVHW-OYRHEFFESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211342   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211342(2,4-dichloro-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi:  0.640nMAssay Description:Binding affinity to human cloned adrenergic alpha1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211342(2,4-dichloro-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to human cloned adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211342(2,4-dichloro-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi:  42nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50211342(2,4-dichloro-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi:  177nMAssay Description:Binding affinity to human cloned adrenergic alpha1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed