BDBM50220524 2-methyl-4-(4-(methylthio)phenyl)-7-(5-(piperidin-1-ylmethyl)pyridin-2-yloxy)-1,2,3,4-tetrahydroisoquinoline::CHEMBL237862

SMILES CSc1ccc(cc1)C1CN(C)Cc2cc(Oc3ccc(CN4CCCCC4)cn3)ccc12

InChI Key InChIKey=UCIGGFFPBMFKPO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220524   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50220524(2-methyl-4-(4-(methylthio)phenyl)-7-(5-(piperidin-...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50220524(2-methyl-4-(4-(methylthio)phenyl)-7-(5-(piperidin-...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50220524(2-methyl-4-(4-(methylthio)phenyl)-7-(5-(piperidin-...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity at human histamine H3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed