BDBM50229198 CHEMBL400044::US9096559, 14::[4-(4-amino-biphenyl-3-ylcarbamoyl)-benzyl]-carbamic acid phenyl ester

SMILES Nc1ccc(cc1NC(=O)c1ccc(CNC(=O)Oc2ccccc2)cc1)-c1ccccc1

InChI Key InChIKey=PKKKXJULINTEGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229198   

TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229198(CHEMBL400044 | US9096559, 14 | [4-(4-amino-bipheny...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229198(CHEMBL400044 | US9096559, 14 | [4-(4-amino-bipheny...)
Affinity DataIC50:  320nMAssay Description:Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...More data for this Ligand-Target Pair
In DepthDetails US Patent