BDBM50231785 CHEMBL4064603::US11725000, Compound 152

SMILES COc1ccc(Cn2cc(ccc2=O)-c2cc(nc(n2)S(=O)(=O)CCCC(=O)N2CCCC2)C(F)(F)F)cc1OC

InChI Key InChIKey=RTLBVKTXKWCWQH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231785   

TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
National Institute of Biological Sciences, Beijing

US Patent
LigandPNGBDBM50231785(CHEMBL4064603 | US11725000, Compound 152)
Affinity DataEC50:  5.01E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
National Institute of Biological Sciences, Beijing

US Patent
LigandPNGBDBM50231785(CHEMBL4064603 | US11725000, Compound 152)
Affinity DataEC50:  27nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed