BDBM50232351 CHEMBL4100664

SMILES CN(C)Cc1c(C)n(Cc2ccc(cc2)C(=O)NO)c2ccccc12

InChI Key InChIKey=AWFYSKUENHXUOS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232351   

TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50232351(CHEMBL4100664)
Affinity DataIC50:  9.73E+3nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 expressed in Sf21 cells using RHKK(Ac) as substrate after 60 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50232351(CHEMBL4100664)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using RHKK(Ac) as substrate after 90 mins by fluorimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50232351(CHEMBL4100664)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length human recombinant C-terminal GST-tagged HDAC2 expressed in insect cells using RHKK(Ac) as substrate after 60 mins by fluori...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed