BDBM50232425 CHEMBL4061639

SMILES Cn1ncc2cc(ccc12)C(=O)Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=ISZVIYGCASWHFG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50232425   

TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232425(CHEMBL4061639)
Affinity DataKi:  0.290nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232425(CHEMBL4061639)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232425(CHEMBL4061639)
Affinity DataIC50:  0.661nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232425(CHEMBL4061639)
Affinity DataIC50:  0.662nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232425(CHEMBL4061639)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOB inhibitor selegili...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed