BDBM50232427 CHEMBL4070309

SMILES Cn1ncc2cc(ccc12)C(=O)Nc1ccc(F)c(F)c1

InChI Key InChIKey=MDOHBHVKAWMFFN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232427   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232427(CHEMBL4070309)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232427(CHEMBL4070309)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232427(CHEMBL4070309)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232427(CHEMBL4070309)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOB inhibitor selegili...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed