BDBM50234942 CHEMBL4093233

SMILES CNc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=ACZYSEPOODWZET-UHFFFAOYSA-N

Data  4 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234942   

TargetHistone acetyltransferase KAT2B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234942(CHEMBL4093233)
Affinity DataIC50:  2.00E+4nMAssay Description:Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 4(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50234942(CHEMBL4093233)
Affinity DataIC50:  1.26E+5nMAssay Description:Binding affinity to BRD4 (1) (unknown origin) N-terminal bromodomain by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone acetyltransferase KAT2B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234942(CHEMBL4093233)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity to PCAF (unknown origin) N-terminal bromodomain by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 9(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50234942(CHEMBL4093233)
Affinity DataIC50:  2.51E+4nMAssay Description:Binding affinity to BRD9 (unknown origin) N-terminal bromodomain by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)