BDBM50235593 CHEMBL4062046
SMILES Cn1nc(O)c(n1)C(=O)Nc1c(F)c(F)c(-c2ccccc2)c(F)c1F
InChI Key InChIKey=NRGHNOMCGATBLG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50235593
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair