BDBM50237948 (E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-mercapto-4-oxo-1-phenyl-1,2,3,4-tetrahydropyrimidine-5-carbonitrile::2-{2-[5-(4-chlorophenyl)furan-2-yl]vinyl}-6-mercapto-4-oxo-1-phenyl-1,2,3,4-tetrahydropyrimidine-5-carbonitrile::CHEMBL401371
SMILES Clc1ccc(cc1)-c1ccc(\C=C\C2NC(=O)C(C#N)C(=S)N2c2ccccc2)o1
InChI Key InChIKey=DMCDPFUYYONCMD-ACCUITESSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50237948
Affinity DataKi: 2.92E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University of Pittsburgh
Curated by ChEMBL
University of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University of Pittsburgh
Curated by ChEMBL
University of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair