BDBM50238074 CHEMBL4075003
SMILES Cc1ccc(F)c(c1)-c1cc(Nc2ccnc3cnn(CC(N)=O)c23)c(C)cn1
InChI Key InChIKey=RCYOPQWQJUQFLX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50238074
Affinity DataEC50: 501nMAssay Description:Inhibition of ALK5 in human Calu6 cells assessed as reduction in Smad2/3 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant N-terminal GST tagged human ALK5 (200 to 503 residues) expressed in baculovirus expression system using FAM-NH2-KVLTQMGSPSI...More data for this Ligand-Target Pair