BDBM50239654 CHEMBL4104071

SMILES COc1ccc(cc1C(O)=O)-c1cc(cc(c1)C1(C(C)C)c2c(C)[nH]nc2OC(N)=C1C#N)C(F)(F)F

InChI Key InChIKey=IMHXCOXLRHCUAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239654   

TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239654(CHEMBL4104071)
Affinity DataIC50:  77nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed