BDBM50240491 CHEMBL4065316::US9969724, Example 11

SMILES Cc1ncn(n1)-c1ccc(C(=O)N[C@@H]2CCN(C2)c2ncc(Cl)c3c(N)noc23)c(Cl)c1

InChI Key InChIKey=UHUFYIGHVDRSKL-LLVKDONJSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240491   

TargetCoagulation factor X(Human)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240491(CHEMBL4065316 | US9969724, Example 11)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50240491(CHEMBL4065316 | US9969724, Example 11)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50240491(CHEMBL4065316 | US9969724, Example 11)
Affinity DataIC50:  33nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed