BDBM50240899 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chromen-4-one::CHEMBL165064::cid_5280862::kaempferol-3-O-methyl ether

SMILES COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)cc1

InChI Key InChIKey=VJJZJBUCDWKPLC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240899   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50240899(5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...)
Affinity DataIC50:  5.41E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50240899(5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...)
Affinity DataIC50:  1.09E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Universidad Nacional De C£Rdoba

Curated by ChEMBL
LigandPNGBDBM50240899(5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240899(5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...)
Affinity DataIC50:  3.62E+4nMAssay Description:Inhibition of human CYP3A4 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240899(5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of human CYP2D6 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed