BDBM50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone

SMILES c1ccc2c(c1)NC(=O)N2CCCN3CCC(CC3)N4c5ccc(cc5NC4=O)Cl

InChI Key InChIKey=FGXWKSZFVQUSTL-UHFFFAOYSA-N

Data  31 KI  23 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 50241107   

TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.530nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.610nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.720nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  0.720nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at Sprague-Dawley rat striatum membrane D2 receptor assessed as inhibition of dopamine stimulated [35S]GTPgammaS binding measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  1.30nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 2.68nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 2.80nMAssay Description:Tested for its affinity towards D2 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Rabbit)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 3.40nMAssay Description:The functional antagonist assay was performed as described in Payne, S. L et al. (2002) J. Neurochem., 82: 1106-1117, hereby incorporated by referenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rabbit)
University of California

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  4.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 5.20nMAssay Description:In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  7.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  7.5nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  9.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 13.6nMAssay Description:Inhibition of the binding of radioligand [3H]spiperone to dopamine receptor D2 in rat brain synaptic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetD(3) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  27.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 57.5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 100nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 162nMAssay Description:K+ channel blocking activity in human embryonic kidney cells expressing HERG Kv11.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 162nMAssay Description:Inhibition of human voltage-gated potassium channel subunit Kv11.1 (ERG K+ channel) in open stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 162nMAssay Description:Inhibition of human ERG in MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 162nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 162nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  294nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H]GR-113808 to 5-hydroxytryptamine 4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAldehyde oxidase(Human)
Washington State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
University of Nebraska

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  2.04E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details
PubMed
TargetMultidrug and toxin extrusion protein 1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKd:  8.80E+3nMAssay Description:Binding affinity to RXRalpha-LBD (unknown origin) measured up to 120 sec by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetD(1A) dopamine receptor(Rat)
UniversitÉ

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
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