BDBM50242509 CHEMBL4068937

SMILES C[C@H](c1cccc2CCNCc12)n1c2ccc(cc2oc1=O)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=WPLZOHYVBARFAX-GFCCVEGCSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242509   

TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50:  31nMAssay Description:Inhibition of NaV1.7 channel in human DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50:  29nMAssay Description:Inhibition of Nav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of NaV1.7 channel in rat DRG neurons assessed as reduction of TTX-sensitive sodium current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50:  21nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50:  82nMAssay Description:Inhibition of NaV1.7 channel in mouse DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed