BDBM50243440 (-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]hept-2-yl)-2,2,4-trimethyl 2,5-dihydro-(1H)-6-oxa-1-aza-chrysen::CHEMBL507701

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)cc(F)c4O[C@@H]([C@H]4CCC[C@@]5(C)O[C@@H]45)c3c12

InChI Key InChIKey=ZQAXPAQOUWPHMI-PYTIWUIXSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243440   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed