BDBM50243604 (S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbonitrile::CHEMBL461912

SMILES NCCCC[C@H](N)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=BEXSRKUIBIGLOG-UWVGGRQHSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50243604   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50243604((S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbo...)
Affinity DataKi:  5.20nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243604((S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50:  577nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50243604((S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243604((S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50:  340nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243604((S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50:  118nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50243604((S)-1-((S)-2,6-diaminohexanoyl)pyrrolidine-2-carbo...)
Affinity DataIC50:  320nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed