BDBM50252256 CHEMBL4064806

SMILES COc1ccccc1NC(=S)NCCN(C)C

InChI Key InChIKey=WGGARZSAXKSVFS-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50252256   

TargetAcetylcholinesterase(Human)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252256(CHEMBL4064806)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293F cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252256(CHEMBL4064806)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of AChE1 in Anopheles gambiae body extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252256(CHEMBL4064806)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252256(CHEMBL4064806)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of recombinant full length Anopheles gambiae AChE1 expressed in baculovirus-infected Sf9 insect cells using acetylthiocholine iodide as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed