BDBM50258280 4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)ethyl)-1-methyl-1H-imidazol-2-amine::CHEMBL494186

SMILES COc1ccc(cc1)C(Cc1cc(ccc1OC)[N+]([O-])=O)c1cn(C)c(N)n1

InChI Key InChIKey=LWIYEMOOCOORBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258280   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258280(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50:  470nMpH: 6.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258280(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50:  470nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258280(4-(2-(2-methoxy-5-nitrophenyl)-1-(4-methoxyphenyl)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of BACE1 (unknown origin) by sAPP_NF cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed