BDBM50258586 (R)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-chlorostyryl)benzoic acid::CHEMBL466831

SMILES CC[C@@H](C)c1onc(c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=QVIHYKVCLQHDII-SXSDINLZSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258586   

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258586((R)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxa...)
Affinity DataEC50:  93nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258586((R)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxa...)
Affinity DataEC50:  105nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed