BDBM50259656 CHEMBL4089402

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)N1CCc2ccccc2C1)B(O)O

InChI Key InChIKey=XAITXWKIZVTOCT-VXKWHMMOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259656   

TargetProteasome subunit beta type-2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50259656(CHEMBL4089402)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate after 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50259656(CHEMBL4089402)
Affinity DataIC50:  0.000200nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50259656(CHEMBL4089402)
Affinity DataIC50:  20nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate after 2 hrs by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed