BDBM50259940 2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-cyclohexadine-1,4-one::CHEMBL442564::CHEMBL470129

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6]-1=[#6]-[#6](=O)-[#6]=[#6](-[#6])-[#6]-1=O

InChI Key InChIKey=VDDALGSXMJYSIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259940   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Heinrich-Heine-UniversitäT DüSseldorf

Curated by ChEMBL
LigandPNGBDBM50259940(2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50259940(2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50259940(2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-...)
Affinity DataIC50:  6.43E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed