BDBM50260298 CHEMBL4075687

SMILES NCc1c(c(C(O)=O)c2ccccn12)-c1ccccc1

InChI Key InChIKey=VMUJASMKVZSIID-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260298   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50260298(CHEMBL4075687)
Affinity DataKi:  920nMAssay Description:Non noncompetitive inhibition of human COX-2 preincubated for 5 mins followed by arachidonic acid substrate addition by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50260298(CHEMBL4075687)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of human COX-2 preincubated for 5 mins followed by arachidonic acid substrate addition by colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50260298(CHEMBL4075687)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by arachidonic acid substrate addition by colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed