BDBM50260355 CHEMBL2063071

SMILES Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](COC(=O)CCCCCCCCCCC(=O)OC[C@H]3O[C@H](C[C@@H]3N=[N+]=[N-])n3cc(C)c(=O)[nH]c3=O)O2)c(=O)[nH]c1=O

InChI Key InChIKey=FDWJEINFFHQCPE-XOGRSFEHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260355   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260355(CHEMBL2063071)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/FLV1000 cells assessed as increase in calcein-AM accumulation incubated for 10 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260355(CHEMBL2063071)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human ABCG2 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260355(CHEMBL2063071)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of human MDR1 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed