BDBM50262762 2,4-Diamino-5-isopropyl-6-(2',6'-dimethylphenylsulfanyl)-7Hpyrrolo[2,3-d] pyrimidine::CHEMBL478192
SMILES CC(C)c1c(Sc2c(C)cccc2C)[nH]c2nc(N)nc(N)c12
InChI Key InChIKey=BTJJARTUWGTJNI-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50262762
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair