BDBM50267976 (S)-3-Amino-1-biphenyl-4-yl-4-(1H-imidazol-4-yl)-butan-2-one; dihydrochloride::(S)-3-amino-1-(biphenyl-4-yl)-4-(1H-imidazol-4-yl)butan-2-one dihydrochloride::CHEMBL483668

SMILES N[C@@H](Cc1cnc[nH]1)C(=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HZXVCCSMFVQNKW-SFHVURJKSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267976   

TargetHistidinol dehydrogenase, chloroplastic(Brassica oleracea var. capitata)
TBA

Curated by ChEMBL
LigandPNGBDBM50267976((S)-3-Amino-1-biphenyl-4-yl-4-(1H-imidazol-4-yl)-b...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistidinol dehydrogenase, chloroplastic(Brassica oleracea var. capitata)
TBA

Curated by ChEMBL
LigandPNGBDBM50267976((S)-3-Amino-1-biphenyl-4-yl-4-(1H-imidazol-4-yl)-b...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistidinol dehydrogenase(Brucella suis)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50267976((S)-3-Amino-1-biphenyl-4-yl-4-(1H-imidazol-4-yl)-b...)
Affinity DataIC50:  12.5nMAssay Description:Inhibition of Brucella suis histidinol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistidinol dehydrogenase(Brucella suis)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50267976((S)-3-Amino-1-biphenyl-4-yl-4-(1H-imidazol-4-yl)-b...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Brucella suis histidinol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed