BDBM50268463 CHEMBL502411::c[L-Phe-D-pro-L-Phe-D-trp]
SMILES O=C1N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]12
InChI Key InChIKey=GIZJWWQFOGQPRY-RRGQHJHPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50268463
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]diprenorphine from rat KOP stably expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]diprenorphine from rat cloned KOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Displacement of [3H]DAMGO from rat cloned MOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Displacement of [3H]DAMGO from rat MOP stably expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.91E+3nMAssay Description:Displacement of [3H]DPDPE from mouse cloned DOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.19E+3nMAssay Description:Displacement of [3H]DPDPE from mouse DOP stably expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human cloned kappa opioid receptor assessed as inhibition of 50 nM U50488H-stimulated GTPgammaS binding by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human cloned mu opioid receptor assessed as inhibition of 100 nM loperamide-stimulated GTPgammaS binding by cell based assayMore data for this Ligand-Target Pair