BDBM50269555 CHEMBL4060757
SMILES Nc1nccn2c(nc(-c3ccc(cc3F)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@H]1CN(CCO1)C1CCOCC1
InChI Key InChIKey=GZYUJXFTHLKPAK-OAQYLSRUSA-N
Data 18 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50269555
Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant full-length His6-tagged BTK (unknown origin) expressed in baculovirus infected Sf9 cells using biotinylated A5 peptide as s...More data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 399nMAssay Description:Inhibition of LYNB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 665nMAssay Description:Inhibition of CSK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of PTK6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of FRK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human ERG by [35S]-MK499 displacement or iKr channel assayMore data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in anti-IgM-induced MIP1betaMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of YES1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of SRMS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair