BDBM50273856 2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydroxy-2-methylpropyl)-5-methylthiazol-4(5H)-one::CHEMBL461878

SMILES C[C@H](NC1=NC(=O)C(C)(CC(C)(C)O)S1)c1ccc(F)cc1

InChI Key InChIKey=UWEKJVSDSPQIOU-VQVVDHBBSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273856   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50273856(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydroxy-...)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50273856(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydroxy-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed