BDBM50278650 CHEMBL470218::N7-(3-chloro-4-fluorophenyl)-N2-(4-(2-(dimethylamino)ethyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES CN(C)CCc1ccc(Nc2nc3ncnc(Nc4ccc(F)c(Cl)c4)c3s2)cc1

InChI Key InChIKey=DKDKYLIXOSFJHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278650   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278650(CHEMBL470218 | N7-(3-chloro-4-fluorophenyl)-N2-(4-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed