BDBM50278701 (S)-(1-(4-(7-(3-chloro-4-fluorophenylamino)thiazolo[4,5-d]pyrimidin-2-ylamino)benzyl)pyrrolidin-2-yl)methanol::CHEMBL511990

SMILES OC[C@@H]1CCCN1Cc1ccc(Nc2nc3ncnc(Nc4ccc(F)c(Cl)c4)c3s2)cc1

InChI Key InChIKey=NBTIZPGKEWLXFV-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278701   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278701((S)-(1-(4-(7-(3-chloro-4-fluorophenylamino)thiazol...)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed