BDBM50282970 2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-pentanoic acid methyl ester::CHEMBL301642

SMILES CC(=O)OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1

InChI Key InChIKey=XRTNIJWWOGBHSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282970   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282970(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Affinity DataIC50:  46nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282970(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Affinity DataIC50:  227nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282970(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Affinity DataIC50:  504nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article