BDBM50284514 CHEMBL4166604

SMILES CC(Oc1ccnc(Nc2cnn(C)c2)c1)c1cccc(c1)C(=O)NCc1ccc(C)cc1

InChI Key InChIKey=VOUVHMKMTMUHHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284514   

TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284514(CHEMBL4166604)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284514(CHEMBL4166604)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed