BDBM50292575 8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one::CHEMBL303846::XANTHYLETIN::cid_65188

SMILES CC1(C)Oc2cc3oc(=O)ccc3cc2C=C1

InChI Key InChIKey=QOTBQNVNUBKJMS-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50292575   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataKi:  7.51E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataKi:  8.36E+3nMAssay Description:Inhibition of human carbonic anhydrase 13 preincubated for 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataKi:  9.18E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataKi:  2.57E+4nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataIC50:  1.95E+5nMAssay Description:Inhibitory concentration against glyceraldehyde-3-phosphate dehydrogenase was determined as log 1/IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain H37Rv))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataIC50: >1.11E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAcetylcholinesterase(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50292575(8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one | CHEMB...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of AChE by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed