BDBM50292846 4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassium Salt::CHEMBL460895

SMILES [O-]P([O-])(=O)C(CCCc1ccc(cc1)-c1ccccc1)P([O-])([O-])=O

InChI Key InChIKey=UQVFFWAGEQWWMP-UHFFFAOYSA-J

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292846   

Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50292846(4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassiu...)
Affinity DataKi:  1nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50292846(4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassiu...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21 (DE3) cells assessed as formation of 1,10-dioic acid metabolite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50292846(4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassiu...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed