BDBM50298800 (+/-)-5-(3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-ynyl)-6-methylpyrimidine-2,4-diamine::Biphenyl antifolate, 3::CHEMBL584391::US8853228, 141
SMILES COc1cc(cc(c1)-c1ccc(C)cc1)C(C)C#Cc1c(C)nc(N)nc1N
InChI Key InChIKey=QVXYJVHNRPNRJL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50298800
Affinity DataIC50: 0.610nMAssay Description:Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third
generation analogs were evaluated in enzyme inhibition assays, assessed
for S. aur...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third
generation analogs were evaluated in enzyme inhibition assays, assessed
for S. aur...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as susbtrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human DHFR assessed as rate of NADPH consumption using dihydrofolate as susbtrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third
generation analogs were evaluated in enzyme inhibition assays, assessed
for S. aur...More data for this Ligand-Target Pair