BDBM50299363 CHEMBL575555::N2-benzyl-6-(piperazin-1-yl)-N4-(pyridin-4-yl)-1,3,5-triazine-2,4-diamine

SMILES C(Nc1nc(Nc2ccncc2)nc(n1)N1CCNCC1)c1ccccc1

InChI Key InChIKey=ISYXVFFEJOZHOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299363   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299363(CHEMBL575555 | N2-benzyl-6-(piperazin-1-yl)-N4-(py...)
Affinity DataIC50:  400nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed