BDBM50299731 CHEMBL578422::N-Cyclopropylmethyl-14beta-[4'-chlorophenylpropioloylamino]-7,8-dihydronorcodeinone

SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)C#Cc1ccc(Cl)cc1

InChI Key InChIKey=CDKZODPLDWSATB-QVDUQQMDSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299731   

TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50299731(CHEMBL578422 | N-Cyclopropylmethyl-14beta-[4'-chlo...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50299731(CHEMBL578422 | N-Cyclopropylmethyl-14beta-[4'-chlo...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50299731(CHEMBL578422 | N-Cyclopropylmethyl-14beta-[4'-chlo...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]DPDPE from human recombinant delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50299731(CHEMBL578422 | N-Cyclopropylmethyl-14beta-[4'-chlo...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed