BDBM50309931 6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-tetraaza-tricyclo[11.11.2.0*3,7*]hexacos-10-yl)-hexanoic acid hydroxyamide::CHEMBL589311

SMILES ONC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@@H]2CCCCCCCCCCC[C@@H](NC1=O)C(=O)N2

InChI Key InChIKey=TVNZWPOEHUTSFV-WZYRSQIMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309931   

TargetHistone deacetylase 1(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mouse)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of recombinant human HDAC4 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
Graduate School of Life Science and Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50309931(6-((1S,7R,10S,13R)-2,8,11,26-Tetraoxo-3,9,12,25-te...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed