BDBM50312629 CHEMBL1088736::Octanedioic Acid-{3-[1-(3,5-Bis(hydroxymethyl)phenyl)-1H-[1,2,3]-triazol-4-yl]phenyl}amide-Hydroxyamide
SMILES OCc1cc(CO)cc(c1)-n1cc(nn1)-c1cccc(NC(=O)CCCCCCC(=O)NO)c1
InChI Key InChIKey=DAFYMIICLGKZQP-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50312629
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 27.8nMAssay Description:Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair