BDBM50316691 CHEMBL1096991::N-[2-(7-{4-[8-(2-(2-Furoyl)aminoethyl)naphthalen-2-yloxy]butoxy}naphthalen-1-yl}ethyl]acetamide

SMILES CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(=O)c5ccco5)c4c3)cc12

InChI Key InChIKey=JPSYHUKTMCNWPA-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316691   

TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316691(N-[2-(7-{4-[8-(2-(2-Furoyl)aminoethyl)naphthalen-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316691(N-[2-(7-{4-[8-(2-(2-Furoyl)aminoethyl)naphthalen-2...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316691(N-[2-(7-{4-[8-(2-(2-Furoyl)aminoethyl)naphthalen-2...)
Affinity DataKi:  0.640nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50316691(N-[2-(7-{4-[8-(2-(2-Furoyl)aminoethyl)naphthalen-2...)
Affinity DataKi:  12nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed