BDBM50318985 1-(9H-carbazol-4-yloxy)-3-(4-benzylpiperidin-1-yl)propan-2-ol::CHEMBL1086542

SMILES OC(COc1cccc2[nH]c3ccccc3c12)CN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=FNPRERNONGSACT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318985   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318985(1-(9H-carbazol-4-yloxy)-3-(4-benzylpiperidin-1-yl)...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]cyanopindolol from human adrenergic beta2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318985(1-(9H-carbazol-4-yloxy)-3-(4-benzylpiperidin-1-yl)...)
Affinity DataKi:  14nMAssay Description:Antagonist activity at human adrenergic beta-1 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50318985(1-(9H-carbazol-4-yloxy)-3-(4-benzylpiperidin-1-yl)...)
Affinity DataKi:  230nMAssay Description:Antagonist activity at human adrenergic beta3 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed